Systemic Formulas DREM is a natural sleep aid designed to promote deep, restful sleep and support healthy sleep cycles. DREM combines calming botanicals like valerian root, passionflower, and skullcap with neurotransmitter-supporting nutrients such as GABA and 5-HTP. This formula helps relax the mind, reduce stress, and encourage restorative sleep—without leaving you groggy in the morning. Ideal for those struggling with occasional sleeplessness, DREM promotes a sense of calm and relaxation for better nightly rest.